Professor Stephen Curry
Dr Humberto Fernandes
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Welcome to the Curry Lab home page
From here you can find out about our research (see below) or use the navigation bar above to read the latest news from the lab or to learn more about how we go about our science. Feedback is always welcome!
We use X-ray crystallography to see what the molecules of life look like and figure out how they work. Our main focus is on the molecular details of how certain RNA viruses cause infection and disease. For example, we have worked on cellular RNA-binding proteins such as PTB, La and Ebp1 that are press-ganged to help with viral translation. We are also studying viral proteins from picornaviruses (e.g. foot-and-mouth diseases virus (FMDV)) and caliciviruses (e.g. murine norovirus). Read more...
Our investigations have also encompassed structural analysis of protein-drug interactions. In particular, our work on human serum albumin (HSA), an abundant blood protein that binds and affects the action of many drugs, helped to reveal the structural basis of its remarkably versatile binding capacity. Read more...
Our lab is one of many here that are part of the Imperial College Centre for Structural Biology (CSB).
The Science is Vital Campaign launched in Sept 2010 to fight the
threat of cuts in the UK science budget.
Read about the campaign
The libel reform campaign launched in 2009 to change the law on defamation, which was being used to stifle open discussion of many
scientific matters. In April 2013 Campaign finally secured
a new act of parliament that offers significantly better protection to scientists and science writers.
You can read about it here.
18 May 2013