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Curry Lab
Biophysics Section |
Group Members/VisitorsProfessor Stephen Curry
Dr Humberto Fernandes
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Welcome to the Curry Lab home pageFrom here you can find out about our research (see below) or use the navigation bar above to read the latest news from the lab or to learn more about how we go about our science. Feedback is always welcome! Research InterestsWe use X-ray crystallography to see what the molecules of life look like and figure out how they work. Our main focus is on the molecular details of how certain RNA viruses cause infection and disease. For example, we have worked on cellular RNA-binding proteins such as PTB, La and Ebp1 that are press-ganged to help with viral translation. We are also studying viral proteins from picornaviruses (e.g. foot-and-mouth diseases virus (FMDV)) and caliciviruses (e.g. murine norovirus). Read more... Our investigations have also encompassed structural analysis of protein-drug interactions. In particular, our work on human serum albumin (HSA), an abundant blood protein that binds and affects the action of many drugs, helped to reveal the structural basis of its remarkably versatile binding capacity. Read more... Our lab is one of many here that are part of the Imperial College Centre for Structural Biology (CSB). For a more personal take on science and structural biology, read about my writing and video work. Or listen to me being interviewed by Emma Tobin for the Thinking about Science podcast (Nov 2012).
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18 May 2013 |
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