Welcome to the Curry Lab home page

From here you can find out about our research (see below) or use the navigation bar above to read the latest news from the lab or to learn more about how we go about our science. Feedback is always welcome!

Research Interests

We use X-ray crystallography to see what the molecules of life look like and figure out how they work. Our main focus is on the molecular details of how certain RNA viruses cause infection and disease. For example, we work on cellular RNA-binding proteins such as PTB, La and Ebp1 that are press-ganged to help with viral translation. We also study viral enzymes, such as the 3C protease from foot-and-mouth diseases virus (FMDV). Read more...

Our investigations also encompass protein-drug interactions - to try to understand what makes drugs stick to a particular protein target. Our work on human serum albumin (HSA), an abundant blood protein that binds and affects the action of many drugs, is helping to reveal the structural basis of its remarkably versatile binding capacity. Read more...

Our lab is one of many here that are part of the Imperial College Centre for Structural Biology (CSB).

For a more personal take on science and structural biology, see my blog etc. page.

In Dec 2009 the CSB presented a screening of Naturally Obsessed, a fascinating film about life in a protein crystallography lab. See here for a review.

June 2009: CSB Techniques Workshop on "Protein Sample Characterisation". You can now download the PowerPoint presentations.

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